Description
=99% HPLC and “sterile” claims without verified basis
– CONFIRMED: KP-10 sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (C-terminal amide)
– CONFIRMED: CAS 374683-28-0, MW 1302.5 Da
– SEPARATED: Kisspeptin-10 from Kisspeptin-54, -14, -13 and KISS1 precursor
–
Kisspeptin-10 10mg — Product Identity and Format
Kisspeptin-10 10mg is a research-grade lyophilised preparation of KP-10, the C-terminal decapeptide of the KISS1-derived kisspeptin family. KP-10 has the sequence Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂, with a C-terminal amide modification. Each vial supplied by Core Research contains 10mg of Kisspeptin-10, verified by RP-HPLC to ≥99.0% purity with identity confirmed by ESI-MS. Batch-specific analytical documentation is available through the Core Research CoA Portal.
Kisspeptin-10 (KP-10) is the shortest biologically active isoform of the kisspeptin family. The kisspeptin family includes KP-54, KP-14, KP-13, and KP-10, all derived from the KISS1 gene product by proteolytic processing. KP-10 should not be conflated with KP-54, KP-14, or the full-length KISS1 precursor protein — these are distinct molecular entities with different molecular weights and published research contexts.
Compound Identity
| Attribute | Value | Notes |
|---|---|---|
| Common Names | Kisspeptin-10, KP-10, Metastin(45-54) | C-terminal decapeptide of KISS1; distinct from KP-54, KP-14, KP-13 |
| Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ | 10 amino acids; C-terminal amide (RF-amide motif required for KISS1R binding); verify against batch CoA |
| CAS Number | 374683-28-0 | Kisspeptin-10 (free base); verify salt form against batch CoA |
| Molecular Formula | C63H83N15O13 | Free base |
| Molecular Weight | 1,302.5 Da | Free base (average) |
| Salt Form | Acetate | Research-grade lyophilised preparation; verify against batch CoA |
| Physical Form | White lyophilised powder | Research-grade preparation |
Analytical Specification
| Test Parameter | Method | Specification |
|---|---|---|
| Purity (RP-HPLC) | C18 column, UV 220 nm | ≥99.0% |
| Identity (ESI-MS) | Electrospray ionisation MS | ±0.1 Da of theoretical MW (1,303.5 Da [M+H]⁺) |
| Endotoxin (LAL) | Kinetic turbidimetric LAL | <1.0 EU/mg |
| Appearance | Visual inspection | White lyophilised powder |
Storage and Transport
| Condition | Specification |
|---|---|
| Long-Term Storage | −20°C, protected from light and moisture |
| Stability Period | Stated on the batch-specific CoA |
| Transit | Ambient; cold-chain packaging included for applicable orders |
Batch Documentation
Every batch of Kisspeptin-10 10mg dispatched by Core Research is accompanied by a batch-specific Certificate of Analysis. CoA documents are available via the Certificate of Analysis Portal. For further information on neuroendocrine research peptides, refer to the Neuroregulatory Peptide Research Matrix.
Frequently Asked Questions
What is the difference between Kisspeptin-10 and Kisspeptin-54?
Kisspeptin-10 (KP-10) is the C-terminal decapeptide of the KISS1 gene product (residues 45–54 of the 54-amino-acid kisspeptin). Kisspeptin-54 (KP-54) is the full-length 54-amino-acid peptide. Both share the C-terminal RF-amide motif required for KISS1R binding. KP-10 is the minimal active fragment; KP-54 has a longer N-terminal extension. They are distinct molecular entities with different molecular weights (KP-10: 1,302.5 Da; KP-54: ~6,234 Da) and should not be used interchangeably in research applications.
What is the “metastin” designation?
Metastin is a historical name for kisspeptin-54 (KP-54), used in early publications before the kisspeptin nomenclature was established. The designation “Metastin(45-54)” refers to the C-terminal decapeptide fragment of metastin/KP-54, which corresponds to KP-10. The metastin identifier should not be treated as identical to all commercial KP-10 preparations — verify the exact sequence and molecular weight against the batch CoA for the specific material supplied.
Where can I access the Certificate of Analysis?
Batch-specific CoA documents are available via the Core Research CoA Portal.
Research Use Only. Kisspeptin-10 10mg is supplied by Core Research exclusively for in vitro laboratory research. Not for human or veterinary use. No dosing, administration, fertility-restoration, post-cycle, or hormone-replacement guidance is provided.
Research context
The published literature on this material is summarised in the laboratory guides linked below. This record describes the material as supplied: identity, format, analytics, storage and documentation. It does not describe effects, and none should be inferred from the catalogue category.
For Research Use Only
Kisspeptin-10 is supplied exclusively for in vitro laboratory research. Not for human or veterinary use. No dosing, reconstitution, or administration guidance is provided.
