Description
Component Identity
BPC-157 — Body Protection Compound
| Attribute | Value | Notes |
|---|---|---|
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val | 15 amino acids; free N-terminus, free C-terminus; verify against batch CoA |
| CAS Number | 137525-51-0 | BPC-157 (free acid) |
| Molecular Weight | 1,419.5 Da | Free acid (average) |
| Mass per vial | 5mg | Co-lyophilised with 5mg TB-500 |
TB-500 — Synthetic Thymosin Beta-4 Fragment
| Attribute | Value | Notes |
|---|---|---|
| Sequence | Ac-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ) | Residues 17–23 of thymosin beta-4; N-terminal acetyl; free C-terminus; verify against batch CoA |
| CAS Number | 77591-33-4 | TB-500 (Ac-LKKTETQ); not the same as full-length thymosin beta-4 (CAS 61512-21-8) |
| Molecular Weight | 799.9 Da | Free acid (average) |
| Mass per vial | 5mg | Co-lyophilised with 5mg BPC-157 |
Analytical Specification
| Test Parameter | Method | Specification |
|---|---|---|
| Purity — BPC-157 (RP-HPLC) | C18 column, UV 220 nm | ≥99.0% |
| Purity — TB-500 (RP-HPLC) | C18 column, UV 220 nm | ≥99.0% |
| Identity — Both components (ESI-MS) | Electrospray ionisation MS | Both peptide masses confirmed against theoretical values in single acquisition |
| Endotoxin (LAL) | Kinetic turbidimetric LAL | <1.0 EU/mg |
| Appearance | Visual inspection | White lyophilised powder |
Analytical note: The two-component co-lyophilised format requires independent chromatographic resolution of BPC-157 and TB-500 within the same preparation. Both components are resolved on a C18 column under gradient conditions and quantified by area normalisation. ESI-MS is performed on the combined preparation, with both peptide masses confirmed against theoretical values in a single acquisition.
Blend Format Research Considerations
The blend format provides a single preparation containing both compounds for research convenience. Researchers should note that the blend format does not imply synergistic activity, complementary mechanisms, or a recommended research protocol. BPC-157 and TB-500 have separate published evidence bases and distinct mechanisms of action. Researchers investigating the individual biochemical properties of either compound should use the standalone vial products. The blend format is appropriate for research designs that require both compounds to be present in the same preparation, such as comparative or combinatorial cell-based assay systems.
Storage and Transport
| Condition | Specification |
|---|---|
| Long-Term Storage | −20°C, protected from light and moisture |
| Stability Period | Stated on the batch-specific CoA |
| Transit | Ambient; cold-chain packaging included for applicable orders |
Batch Documentation
Every batch of BPC-157 / TB-500 Blend 10mg dispatched by Core Research is accompanied by a batch-specific Certificate of Analysis documenting the purity and identity of both components. CoA documents are available via the Certificate of Analysis Portal. For further information on repair biology research compounds, refer to the Repair Research Peptide Comparison guide.
Frequently Asked Questions
What is the difference between this blend and the standalone BPC-157 and TB-500 products?
The blend vial contains 5mg BPC-157 + 5mg TB-500 co-lyophilised in a single vial. The standalone products contain 10mg of a single compound. The blend format is a research convenience preparation — it does not imply synergistic activity or a recommended research protocol. Researchers investigating the individual biochemical properties of either compound should use the standalone products.
Is TB-500 the same as thymosin beta-4?
No. TB-500 (Ac-LKKTETQ, CAS 77591-33-4) is a synthetic heptapeptide corresponding to residues 17–23 of thymosin beta-4 (Tβ4, CAS 61512-21-8). TB-500 is not Tβ4 and should not be described as such. They are distinct molecular entities with different sequences, molecular weights, and published research contexts.
Where can I access the Certificate of Analysis?
Batch-specific CoA documents are available via the Core Research CoA Portal.
Research Use Only. BPC-157 / TB-500 Blend 10mg is supplied by Core Research exclusively for in vitro laboratory research. Not for human or veterinary use. No dosing, administration, tissue-repair, or healing-protocol guidance is provided.
Research context
The published literature on this material is summarised in the laboratory guides linked below. This record describes the material as supplied: identity, format, analytics, storage and documentation. It does not describe effects, and none should be inferred from the catalogue category.
For Research Use Only
BPC-157 / TB-500 Blend is supplied exclusively for in vitro laboratory research. Not for human or veterinary use. No dosing, reconstitution, or administration guidance is provided.
