Description
L-Carnitine 600mg/ml — Product Identity and Format
Each vial contains 10ml of solution at a labelled concentration of 600mg/ml, providing a total labelled content of 6,000mg L-carnitine. The solution is supplied in a ready-to-use liquid format. Batch-specific analytical documentation is available through the Core Research CoA Portal.
L-Carnitine (3-hydroxy-4-(trimethylammonio)butanoate) is a quaternary ammonium compound that plays an essential role in the transport of long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation. The carnitine palmitoyltransferase (CPT) system — comprising CPT1 (outer mitochondrial membrane) and CPT2 (inner mitochondrial membrane) — catalyses the conjugation and deconjugation of carnitine with fatty acyl-CoA esters, enabling their translocation into the mitochondrial matrix.
Compound Identity and Formulation
| Attribute | Value | Notes |
|---|---|---|
| Common Name | L-Carnitine | 3-hydroxy-4-(trimethylammonio)butanoate; zwitterionic form at physiological pH |
| CAS Number | 541-15-1 | L-Carnitine (free base/zwitterion) |
| Molecular Formula | C7H15NO3 | Free base (zwitterion) |
| Molecular Weight | 161.2 Da | Free base |
| Concentration | 600mg/ml (labelled) | Verify against batch CoA |
| Fill Volume | 10ml | Total labelled content: 6,000mg L-Carnitine per vial |
| Vehicle/Solvent | Aqueous solution | Verify excipients, pH, and preservatives against batch CoA |
| Physical Form | Clear aqueous solution | Ready-to-use liquid format; not a lyophilised material |
Formulation note: L-Carnitine 600mg/ml is a finished aqueous solution, not a lyophilised powder. The applicable analytical methods and stability specifications for a finished liquid formulation differ from those used for lyophilised peptides. Researchers should verify the specific analytical methods, excipient composition, pH, and stability data against the batch-specific Certificate of Analysis before use.
Analytical Specification
| Test Parameter | Method | Specification |
|---|---|---|
| Identity | HPLC with UV detection or LC-MS | Confirmed against L-Carnitine reference standard |
| Concentration | HPLC quantification | 600mg/ml (±tolerance stated on CoA) |
| Appearance | Visual inspection | Clear, colourless to pale yellow aqueous solution |
| pH | pH meter | Stated on batch CoA |
Carnitine Shuttle Biochemistry
The carnitine shuttle is the primary mechanism by which long-chain fatty acyl-CoA esters cross the inner mitochondrial membrane for beta-oxidation.
L-Carnitine availability is a rate-limiting factor in the carnitine shuttle, and its concentration in the cytoplasm and mitochondrial matrix influences the rate of long-chain fatty acid oxidation. In cell-based models, L-Carnitine supplementation is used to study CPT1 and CPT2 activity, mitochondrial fatty-acid oxidation rates, and the relationship between carnitine availability and beta-oxidation flux.
Carnitine Deficiency Research Models
These models are relevant to research into primary carnitine deficiency (SLC22A5 mutations), secondary carnitine deficiency, and the role of carnitine in mitochondrial disease.
Storage and Transport
| Condition | Specification |
|---|---|
| Storage (liquid solution) | 2–8°C, protected from light; do not freeze |
| Stability Period | Stated on the batch-specific CoA |
| Transit | Cold-chain packaging included |
Batch Documentation
Every batch of L-Carnitine 600mg/ml dispatched by Core Research is accompanied by a batch-specific Certificate of Analysis. CoA documents are available via the Certificate of Analysis Portal. For further information on NAD+ and metabolism research compounds, refer to the Metabolism Research Compound Comparison guide and the Supplier Verification and Quality System.
Frequently Asked Questions
Where can I access the Certificate of Analysis?
Batch-specific CoA documents are available via the Core Research CoA Portal.
Research Use Only. L-Carnitine 600mg/ml is supplied by Core Research exclusively for in vitro laboratory research. Not for human or veterinary use. No supplementation, injection, exercise-performance, or weight-management guidance is provided.
Research context
The published literature on this material is summarised in the laboratory guides linked below. This record describes the material as supplied: identity, format, analytics, storage and documentation. It does not describe effects, and none should be inferred from the catalogue category.
For Research Use Only
L-Carnitine 600mg/ml solution is supplied exclusively for in vitro laboratory research. Not for human or veterinary use. No dosing, administration, injection, or supplementation guidance is provided.
