Description
CJC / Ipamorelin Refill 10mg — Dual GH Secretagogue Blend Refill Cartridge for the Core Research Peptide Pen v3
Each refill cartridge contains a total of 10mg of the lyophilised blend (CJC-1295 and Ipamorelin in a defined ratio), verified by RP-HPLC to a minimum purity of ≥99.0% for each component, with molecular identities confirmed by ESI-MS. Endotoxin content is certified at <1.0 EU/mg by kinetic turbidimetric LAL assay. A batch-specific Certificate of Analysis is included with every order.
Compound Identity & Molecular Data
| Parameter | Value |
|---|---|
| Compound 1 | CJC-1295 (without DAC) — GHRH(1-29) analogue |
| CJC-1295 MW | 3,367.97 Da (free base, monoisotopic) |
| CJC-1295 CAS | 863288-34-0 |
| Compound 2 | Ipamorelin — GHSR-1a selective agonist pentapeptide |
| Ipamorelin MW | 711.87 Da (free base, monoisotopic) |
| Ipamorelin CAS | 170851-70-4 |
| Total Quantity per Cartridge | 10 mg (blend; defined CJC-1295 : Ipamorelin ratio) |
| Primary Receptors | GHRHR (CJC-1295); GHSR-1a (Ipamorelin) |
| Research Classification | Dual GH secretagogue blend; pulsatile GH release; GH axis research |
Analytical Release Testing — Refill Cartridge Specification
| Test | Method | Specification | Notes |
|---|---|---|---|
| Purity (each component) | RP-HPLC (C18, UV 220 nm) | ≥99.0% | Acetonitrile/water gradient; TFA modifier |
| Identity (each component) | ESI-MS | Confirmed ±0.1 Da | Electrospray ionisation mass spectrometry |
| Endotoxin | Kinetic turbidimetric LAL | <1.0 EU/mg | USP <85> compliant method |
| Residual Moisture | Karl Fischer titration | <5.0% | Coulometric KF; lyophilisation quality indicator |
| Total Quantity per Cartridge | Gravimetric | 10 mg ± 5% | Lyophilised acetate salt blend; net peptide content |
| Compatible Device | — | Core Research Peptide Pen v3 | Use with 4mm 31G pen needles |
Reconstitution & Handling Guidance
CJC / Ipamorelin Refill cartridges are supplied in lyophilised form and must be reconstituted before use. For use with the Core Research Peptide Pen v3, reconstitute the cartridge with bacteriostatic water to the desired concentration. A typical reconstitution is 2ml bacteriostatic water per 10mg cartridge to yield a 5mg/ml total peptide solution. Allow the lyophilised cake to dissolve completely by gentle swirling — do not vortex. The reconstituted solution should be clear and colourless; discard if particulate matter or discolouration is observed.
Storage & Stability
| Condition | Temperature | Duration | Notes |
|---|---|---|---|
| Lyophilised cartridge (long-term) | −20°C | ≥24 months | Desiccated; protect from light and moisture |
| Lyophilised cartridge (short-term) | 2–8°C | Up to 4 weeks | Desiccated; suitable for active research use |
| Reconstituted in bacteriostatic water | 2–8°C | Up to 28 days | Benzyl alcohol preservative extends stability |
| Reconstituted aliquots (extended) | −80°C | Up to 12 months | Single-use aliquots; avoid repeated freeze-thaw cycles |
Frequently Asked Questions
What is the ratio of CJC-1295 to Ipamorelin in the blend?
The CJC-1295 : Ipamorelin ratio in the blend is specified on the batch Certificate of Analysis included with each order. The ratio is formulated to reflect commonly used pre-clinical research protocols. Researchers requiring a custom ratio should contact Core Research directly.
Why is the without-DAC form of CJC-1295 used in this blend?
CJC-1295 without DAC produces a shorter-acting, pulsatile GH release pattern that more closely mirrors endogenous GHRH signalling, making it more appropriate for research into physiological GH axis regulation. Researchers specifically investigating the pharmacology of the DAC modification should request the with-DAC form separately.
Is a Certificate of Analysis provided with each refill?
Yes. A batch-specific Certificate of Analysis documenting RP-HPLC purity for each component, ESI-MS identity confirmation, LAL endotoxin result, and Karl Fischer moisture content is included with every CJC / Ipamorelin Refill 10mg order.
Related Research Guides
Standard Format
CJC-1295 / Ipamorelin 10mg Pen
Related Refill
Tesamorelin Refill 10mg
Compatible Device
Reusable Metal Peptide Pen v3
Reconstitution
Bacteriostatic Water 10ml
Pen Needles
GlucoRx Pen Needles 4mm 31G
Category
All Refill Cartridges
Research context
The published literature on this material is summarised in the laboratory guides linked below. This record describes the material as supplied: identity, format, analytics, storage and documentation. It does not describe effects, and none should be inferred from the catalogue category.
For Research Use Only — Not for Human or Veterinary Use
CJC / Ipamorelin Refill 10mg is supplied exclusively for in vitro and pre-clinical in vivo research use with the Core Research Reusable Metal Peptide Pen v3. This product has not been evaluated by the MHRA, FDA, or any other regulatory authority for safety or efficacy in humans or animals. Purchase confirms the buyer is a qualified researcher.
